biometrics to system genetics


Mutation and the evolution of ageing: from biometrics to system genetics

FREE-DOWNLOAD KA Hughes – … Transactions of the Royal Society B: …, 2010 –
A notable success for evolutionary genetics during the past century was to generate a
coherent, quantitative explanation for an apparent evolutionary paradox: the tendency for multicellular
organisms to show declining fitness with age (senescence, often referred to simply as

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