cancer treatment RESEARCH PAPER 2017
Dendritic Cell Immunotherapy, the Next Step inCancer Treatment
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* Corresponding author: Teunis BH Geijtenbeek, Department of Experimental Immu- nology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. Objective Diagnosing lymphedema is challenging, especially in the early stages (stage 0 or 1; Table 2) of the disease, with varying definitions and objective tools available for diagnostic assessment. The National Lymphedema Network (NLN), the International Society
Addressing the Survivorship Care Needs of Patients Receiving ExtendedCancer Treatment .
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Cancersurvivorship care and research has typically focused on the health care needs of people withcancerfollowing the acute phase oftreatment . Work in this area, however, has faced challenges in identifying whentreatmentis complete for many forms ofcancer .
Pharmacogenetics: Focus on BreastCancer Treatment
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The success or failure ofcancer treatmentis based upon various factors including age, gender, stress, and disease type. The phenotypic changes results from variation in genetic makeup of the individuals and environmental factors, and use of drugs [1]. Further, these Cancer Treatment
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Abstract Background: Endometrial cancer is the fourth most prevalent cancer in Canadian women. Radiotherapy (RT) is frequently recommended as an adjuvant treatment. There is a high prevalence (> 80%) of urinary incontinence (UI) after RT. It is plausible that UI is
Tamoxifen metabolism in breastcancer treatment : Taking the focus off the CYP2D6 gene
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Tamoxifen (TAM) has been widely used to treat estrogen receptor (ER)-positive breast cancer , and has led to reduction of 50% in the annual recurrence rate and 30% in breast cancermortality after 5 years oftreatment . 1 The prodrug TAM is a selective ER modulator
Knowledge, attitude and perceptions of Muslimcancerpatients regardingcancer treatmentduring Ramadan: Results from a tertiary care hospital Karachi
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Abstract Objective: To assess the knowledge and attitude of Muslimcancerpatients regardingcancer treatmentduring Ramadan. Methods: This cross-sectional study was conducted at the Aga Khan University Hospital, Karachi, from July to August 2015, and
Differentiation Therapy by Extracts of Embryo Cells: A Possibility forCancer Treatment
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Abstract Various chemical and biochemical differentiation compounds have been shown to revert to normal state several kinds ofcancercells. As embryonic andcancercells present similarities of behavior and phenotype and as regulatory factors in young embryos have
Impact of urologists ownership of radiation equipment in thetreatmentof prostatecancer
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BACKGROUND: Physician practices that offer ancillary medical services may refer their patients for such services, a process known as self-referral. We wanted to evaluate how utilization and cost of care differ for men diagnosed with prostatecancerin a self-referral
A Novel Potential Therapeutic Target as AdjuvantTreatmentforCancer : The Pharmacological Interference on the Ca2+/Camp Cellular Signaling Pathways
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Canceris one of the leading causes of death worldwide: about 12.7 million people worldwide are diagnosed withcancerevery year, and 7.6 million of the diagnosed patients die because of this disease. It is estimated that in 2030, there will be 26 million new cases,
Use of a cognitive computing system fortreatmentof cervicalcancer
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Second, Watson showed different decisions in particular clinical situations. For example, we recommended concurrent chemoradiotherapy for an 80-year old woman with FIGO stage IB1 cervicalcancerwho could not endure radical surgery. However, WFO recommended
Pencil Beam Grid Antenna Array for Hyperthermia BreastCancer TreatmentSystem
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Abstract In this paper, efficient, high gain and pencil beam grid antenna array is proposed for hyperthermia breastcancertherapy system. The proposed antenna bandwidth extends from 4.8 GHz to 4.9 GHz at resonant frequency of 4.86 GHz. This frequency band has been
between Preferred and Actual Participation Roles Increases Satisfaction withTreatmentDecision Making among Japanese Women with BreastCancer
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Abstract Objective: This study investigated the correlation between participation in the treatmentdecision-making process and satisfaction with the process among Japanese women with breastcancer . The influence of sociodemographic and clinical characteristics
Combined Approach of Ligand Targeted and Stimuli-triggered Nanocarriers: a State-of-the-art Strategy forCancer Treatment
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Canceris one of the worlds most devastating diseases and chemotherapy remains one of the basictreatmentmethods. In spite of high cytotoxicity of chemotherapeutics against tumor cells, efficacy is greatly hampered by extensive distribution throughout the body following
FY26 POTENT ANTICANCER: A NEW DRUG APPROACH INCANCER TREATMENT
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ABSTRACT The main aim of the anticancer drugs is to eradicate the presence of malignant cells. The anticancer drugs are classified on the bases of their site of action on a point of biosynthesis pathway of important bio molecules. These classified as follows Alkylating
Early Diagnosis of Lymphedema after BreastCancer Treatment : Bio-Impedance Spectroscopy.
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ABSTRACT Objective: Breastcancer -related lymphedema is an important health problem. The aim of this study is to ensure early diagnosis of patients at risk of developing lymphedema and revealing the predisposing factors. Materials and Methods: Measurements IMPACT OF PHARMACEUTICAL COUNSELLING ONCANCERPATIENTSINFORMATION DESIRE ANDTREATMENTSATISFACTION
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Evaluation based on questionnaires, scoring with 5-point Likert scale: EID = Extent of Information
Desired PS-CaTE = Patient Satisfaction onCancerTreatmentEducation Subcategories:Cancer treatment , Side effects, Information sources, Overall satisfaction CTSQ =CancerTreatment
US panel nod for gene-alteringcancer treatment
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AUS Food and Drug Admi-nistration panel opened a new era in medicine on Wednesday, unanimously recommending that the agency approve the first-evertreatmentthat genetically alters a patients own cells to fightcancer , transforming them into what scientists calla living Abstract Secretory phospholipases A2 (PLA2s) are ubiquitous enzymes taking part in different biological pathways including cell growth and differentiation. Mammalian PLA2s mostly enhance tumor cell proliferation, while snake venom PLA2s (svPLA2s) are capable to
Role of nano-curcumin: Atreatmentforcancer
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Abstract Conventional therapies ofcancercause serious side effects, systemic toxicity, poor quality of life of patients, accompanied with tumor resistance and recurrence which discourage their long term use. Therefore, highly precise anticancer therapies with minimal
A REVIEW ON NANOTECHNOLOGY INCANCER TREATMENT
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ABSTRACT Nanotechnology is the study and use of structures between 1 nanometer and 100 nanometers in size.Canceris the leading cause of death among people younger than 85 years. Nanoparticles that deliver chemotherapy drugs directly tocancercells are under
MSP-Ron signalling incancer treatment
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Lddress correspondence to (Present address): Dr. Takashi KATO Urologic Oncology Branch, Center forCancerResearch, NationalCancerInstitute. National Institutes of Health, Building 10-CRC, MSC 1107, Center Drive, MSC 1107, Bethesda, MD, 20892-1107, USA
Nanosponges: A Novel Targeted Drug Delivery forCancer Treatment
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ABSTRACT Effective Drug delivery at the targeted or specific site is the significant problem which is being faced by the researchers in the anti- cancerformulation. The development of new colloidal, porous, tiny mesh-like carrier called nanosponges with the size 1μm range
What are the optimaltreatmentmodalities according to age group in gastriccancerpatients?
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Cancerin older people has become an increasingly common problem due to the prolonged life expectancy of the general population.Cancer treatmentis challenging but it can be more difficult in geriatric population. Aging is associated with progressive reduction of the bodys Potential impact oftreatmenton the mood of older women of primary breastcancer
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with primary breastcancerRM Parks1, K Cox2, P Howard and KL Cheung1 1School of Medicine
and 2School of Health Sciences, University of Nottingham, UK Page 2. School of Medicine
BackgroundFor primary breastcancertreatmentis surgeryComorbidity, frailty, competitive
When Constipation is not due to Opioids and the Management of Pain is not Proper: Implications inCancer Treatment
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Pain is a frequent symptom in the evolution of acancerpatient, affecting 70% of them in terms of decreasing quality of life.Treatmentshould adapt to type and intensity of pain in order to optimize analgesic control.In this case report we will review different pain types with the use of
The Prognostic Value of Pre- TreatmentLeukocytosis in Patients with Previously Treated, Stage IIIB/IV Non-Small Cell LungCancerTreated with the IGF-1R
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Abstract Background: The aim of the present study was to investigate any prognostic value of pre- treatmentanemia, leukocytosis and thrombocytosis in patients with advanced pretreated NSCLC. Methods: A randomized, multicenter phase II study comparing the IGF-
-utility Analysis Comparing Large Volume Displacement Oncoplastic Surgery to Mastectomy with Free Flap Reconstruction in theTreatmentof BreastCancer
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RESULTS: A total of 99 digits and 69 subjects were included. Two variables were found to be significant in predicting response to initial injection: 1. Multiple affected digits 2. Stage severity. Patients with multiple involved fingers were 5.8 times more likely to have no
Ultrasound contrast-enhanced study as an imaging biomarker for anti- cancerdrugtreatment : preliminary study with paclitaxel in a xenograft mouse tumor model
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Purpose: The purpose of this study was to assess tumor angiogenesis using contrast enhanced ultrasonography (CEUS) of human prostatecancercells (PC3) that were implanted in mice before and after paclitaxel injection. Methods: Twelve mice were injected
miR-331-3p and Aurora Kinase inhibitor II co- treatmentsuppresses prostatecancertumorigenesis and progression.
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ABSTRACT RNA-based therapeutics could represent a new avenue ofcancer treatment . miRNA 331-3p (miR-331-3p) is implicated in prostatecancer(PCa) as a putative tumor suppressor, but its functional activity and synergy with other anti-tumor agents is largely
Nanoceria and Its Perspective inCancer Treatment
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Abstract From the birth of mankind,canceris known as one of the most notorious and deadly diseases human kinds has ever faced on this earth. Many methods and ways are implemented to eliminate this disease and the number is still on the increasing side. Its
Treatmentwith olaparib monotherapy in the maintenance setting significantly improves progression-free survival in patients with platinum-sensitive relapsed
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Eric Pujade-Lauraine,1 Jonathan A Ledermann,2 Richard T Penson,3 Amit M Oza,4 Jacob Korach,5 Tomasz Huzarski,6 Andrés Poveda,7 Sandro Pignata,8 Michael Friedlander,9 and Nicoletta Colombo101Université Paris Descartes, AP-HP, Paris, France; 2University College
SurgicalTreatmentfor T4 OropharyngealCancer
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In Reply We thank Dr Garden1 for his interest and commentary. He brings up 2 general study limitations: the surgical and nonsurgicaltreatmentgroups have certain inherent differences, and the nonsurgicaltreatmentparadigms were heterogeneous. These are
Social Media and Mobile Technology forCancerPrevention andTreatment .
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Given the number of lives affected bycancerand the great potential for optimizing well being via lifestyle changes, patients, providers, health care systems, advocacy groups, and entrepreneurs are looking to digital solutions to enhance patient care and broaden
Intraductal cisplatintreatmentin a BRCA-associated breastcancermouse model attenuates tumor development but leads to systemic tumors in aged female
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In BRCA mutation carriers this risk can increase up to 80%. Currently, bilateral prophylactic mastectomy and prophylactic bilateral salpingo-oophorectomy are the only preventive, albeit radical invasive strategies to prevent breastcancerin BRCA mutation carriers. An alternative
Definition and estimation of osteonecrosis of jaw (ONJ), and optimal duration of antiresorptivetreatmentin bone metastaticcancerpatients: supplementary data from
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To the Editor, In their recent article, Stopeck et al.[1] concluded that denosumab confirms its known safety profile even after longterm exposure, or after switching to it from zoledronic acid, and that osteonecrosis of jaws (ONJ) rates increased with increasing exposure to
Adjuvant S-1 chemotherapy after curative resection of gastriccancerin Chinese patients: assessment oftreatmenttolerability and associated risk factors
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ABSTRACT Introduction: The use of adjuvant chemotherapy with S-1 (tegafur, gimeracil, and oteracil potassium) has been shown to improve the outcome of patients with gastriccancer . There are limited data on the tolerability of S-1 in Chinese patients. In this multicentre -FETOPROTEIN (AFP) AMONG PATIENTS WITH TESTICULARCANCERMAY NOT BE ASSOCIATED WITH RESIDUALCANCEROR NEED FORTREATMENT
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Page 1. MILDLY ELEVATED AFP Article Type: Letter to the Editor Title: MILDLY
ELEVATED SERUM ALPHA-FETOPROTEIN (AFP) AMONG PATIENTS WITH
TESTICULARCANCERMAY NOT BE ASSOCIATED WITH RESIDUALCANCER We very much appreciate the interest Reifsnider et al.[1] have taken in our perspective on the single technology appraisal (STA) of abiraterone acetate (tradename Zytiga®) plus prednisolone (AAP) acetate for thetreatmentof chemotherapynaive metastatic castration-
reverse sequence as first-linetreatmentof hormone-responsive, human epidermal growth factor receptor-2 negative metastatic breastcancerpatients: results of
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ABSTRACT Introduction Although hormonal-therapy is the preferred first-linetreatmentfor hormone-responsive, HER2 negative metastatic breastcancer , no data from clinical trials support the choice between hormonal-therapy and chemotherapy. Methods Patients were
From tumour heterogeneity to advances in precisiontreatmentof colorectalcancer
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Abstract| In recent years, the high heterogeneity of colorectalcancer(CRC) has become evident. Hence, biomarkers need to be developed that enable the stratification of patients with CRC into different prognostic subgroups and in relation to response to therapies,
Utilizing Tumor and Plasma Liquid Biopsy inTreatmentDecision Making for an Estrogen Receptor-Positive Advanced BreastCancerPatient
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Abstract Breastcanceraffects 12% of females in the United States and is the leading cause ofcancerdeath in the female population. Personalized therapy is being used in clinical practice to treat breastcancerbased on tumor molecular profiling, which can be obtained
Combinatorialtreatmentwith polyI: C and anti-IL6 enhances apoptosis and suppresses metastasis of lungcancercells
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ABSTRACT Activation of TLR3 stimulatescancercell apoptosis and triggers secretion of inflammatory cytokines. PolyI: C, a TLR3 agonist, activates immune cells and regresses metastatic lungcancerin vivo. Although polyI: C reportedly kills lung carcinomas, the Examining Bias in Studies of StatinTreatmentand Survival in Patients WithCancer
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OBJECTIVE To emulate a randomized trial of statin therapy initiation that is free of selection bias and immortal-time bias. DESIGN, SETTING, AND PARTICIPANTS We used observational data on 17 372 patients withcancerfrom the Surveillance, Epidemiology, and
A novel small molecule inhibitor of p300/CBP for thetreatmentof castration resistant prostatecancerpreclinical evaluation
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ConclusionsSmall molecule inhibition of the bromo-domain of p300/CBP, leads to down regulation of AR, AR-SV and c-Myc, as well as inhibiting key downstream genes, including PSA and TMPRSS2.CCS1477, a clinical candidate, causes complete tumour growth
Reversible Encephalopathy Following Primary Debulking Surgery in OvarianCancer : Significance of Early Diagnosis andTreatment[Version 1, Awaiting Peer
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Abstract Background: Posterior reversible encephalopathy (PRES) is a neuroradiological clinical entity with generally good prognosis with early diagnosis and intervention. Various risk factors have been described in literature although the pathophysiology is still not Adjuvant therapy for pancreaticcancer : An updated analysis oftreatmentoutcomes in elderly patients using the NationalCancerDatabase (NCDB)
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BackgroundFrom 2004 to 2011, the rates of observation and chemoradiotherapy decreased. In contrast, multi-agent chemotherapy use increased while single-agent chemotherapy remained stable.(Figure 1).Differences in the frequency of adjuvant therapy
Mortality andcancerrisk on long-term antiplatelettreatment : What is known and what we still dont know
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Despite various large-scale clinical trials and particularly large amounts of data coming from different independent studies (1, 2) and meta-analyses (3 5), the optimal duration of dual antiplatelettreatment(DAPT) is still considered unknown for both acute coronary syndrome
Clinical impact of 68Ga-PSMA PET/CT in prostatecancerpatients with rising PSA aftertreatmentwith curative intent: Preliminary analysis of a multidisciplinary
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ABSTRACT Background: To assess the impact of 68 Ga-(HBED-CC)-PSMA (Prostate Specific Membrane Antigen) PET/CT in the clinical management of PCa patients with rising PSA aftertreatmentwith curative intent. 68 Ga-PSMA PET/CT scan is a novel molecular cancersites. The aim of this type of agenda has been to highlight differences in national treatmentapproaches and to raise discussion on their effect on outcome. More importantly,
Image-Guided Radiotherapy Dose Escalation in Intermediate and High RiskCancerProstate Patients and Its Effect onTreatmentToxicity
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Abstract Purpose: To study the effect of escalating radiation dose; in intermediate and high risk prostatecancerpatients; via online image-guidance on acute toxicities. Patients and Methods: thirty-eight prostatecancerpatients were treated by using simultaneous integrated
Use of a genome-wide haploid genetic screen to identifytreatmentpredicting factors: a proof-of-principle study in pancreaticcancer .
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ABSTRACT The ability to develop a comprehensive panel oftreatmentpredicting factors would significantly improve our ability to stratify patients for cytotoxic or targeted therapies, and prevent patients receiving ineffective treatments. We have investigated if a recently
, and antitumor activity of MEDI3726 in patients with metastatic, castration-resistant prostatecancerwho have received priortreatmentwith abiraterone or
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BackgroundProstate-specific membrane antigen (PSMA), a membranebound glutamate carboxypeptidase II, is highly expressed in nearly all prostate cancers regardless of disease stage, metastatic site, and hormone deprivation resistance (1, 2, 3).PSMA expression is
Blood-based and urinary prostatecancerbiomarkers: a review and comparison of novel biomarkers for detection andtreatmentdecisions
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BACKGROUND: The diagnosis of prostatecancer(PCa) is currently based on serum PSA testing and/or abnormal digital rectal examination and histopathologic evaluation of prostate biopsies. The main drawback of PSA testing is the lack of specificity for PCa. To improve Ramaekers et al.[1] describe a review of the single technology appraisal [2] of Janssen Cilags abiraterone acetate (tradename Zytiga®) plus prednisolone (AAP) in chemotherapy naive metastatic castration-resistant prostatecancer(mCRPC) from the perspective of the
Irreversible electroporation for thetreatmentof localized prostatecancer : a summary of imaging findings andtreatmentfeedback
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PURPOSE Imaging plays a crucial role in ablative therapies for prostatecancer(PCa). Irreversible electroporation (IRE) is a newtreatmentmodality used for focaltreatmentof PCa. We aimed to demonstrate what imaging modalities can be used by descriptively Dear Sir, We wish to thank Campagna et al. for their considered appraisal of our work [1] and their insights regarding the role that Electrochemotherapy (ECT) plays in thetreatment of cutaneous metastasis of breastcancer . It is very encouraging to see broader support for Extending letrozoletreatmentto 10 years may prevent recurrent breastcancer
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This randomized, double-blind, placebo-controlled trial assessed the effect of extending dosing of letrozole from 5 years to 10 years in a group of 1,918 postmenopausal women with breast canceracross North America. This study enrolled participants if they had completed 4.5 to 6 years
The effects of the human fetal estrogen estetrol (E4) in healthy men to estimate its potential use for thetreatmentof prostatecancer
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Study ObjectiveA daily dose of 20 mg, 40 mg or 60 mg E4 was well tolerated by healthy men aged 40-70 years. Libido decrease and nipple tenderness were the side effects which were most frequently reported.The observed dose-response related decrease of total and
Falls-risk in senior women after radicaltreatmentof breastcancer
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Abstract Introduction: It is estimated that 35 40% people over the age of 65 experience at least one fall per year; for those over the age of 80 this increases to 50%, and for residents of institutional care facilities, to 60%. Aim of the research: To evaluate the functional capacity
Effects and mechanisms of chloroquine alone and in combination with cisplatin in thetreatmentof human ovariancancercell SKOV3 in vitro
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Abstract: Chloroquine is widely used as an effective and safe anti-malarial agent and has been a hotspot for its potential role incancertherapies recently. Ovariancanceris the most lethal gynecologic malignancy worldwide with chemotherapy drug resistance as a major
Evaluation oftreatmentcompletion note used by the BCCancerAgency Centre for the North
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ABSTRACT Background: After patients receive radiotherapy forcancerin BC,treatment completion notes are sent to their family physicians to documenttreatmentand aid in transitions in care. A study was proposed to determine iftreatmentcompletion notes are
Therapeutic effects and associated adverse events of PD-1 and CTLA-4 pathway inhibitors in thetreatmentof non-small-cell lungcancer : meta-analyses of
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Abstract: Objective: To summarize and compare the therapeutic efficacy of programmed death 1 (PD-1) and cytotoxic T lymphocyte associated antigen 4 (CTLA-4) pathway inhibitors in thetreatmentof non-small-cell lungcancer(NSCLC). Methods: Traditional and network
Unmet Supportive Care Needs of Men With Locally Advanced and Metastatic ProstateCanceron HormonalTreatment
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Background: Men affected by prostatecancerwho are undergoing hormone therapy can endure a range of symptoms that can adversely affect quality of life. Little research has been conducted to date, to understand the specific unmet supportive care needs of this patient group within the
Differential microRNA expression in epithelial cell populations from human prostate: its relevance totreatmentresistance in prostatecancer
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Underline: underlines the text Add note to text: links selected text with a pop-up note Sticky notes To make a note: choose the Sticky Note option and then click on a desired location Changing the name: double-click and choose Options→ Sticky Note Properties→ General→ low volume MPC, who were admitted only to the later part of the study. High-volume disease was defined as visceral organ metastasis and/or≥ 4 bone metastasis of at least one outside We read with interest Bourke et al.s paper on thetreatmentof cutaneous metastases from breastcancer(BC) with electrochemotherapy (ECT)[1]. In a highly pretreated population whose survival from the diagnosis of skin metastases was 36 months ECT proved to be
Melatonin for the prevention andtreatmentofcancer .
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ABSTRACT The epidemiological studies have indicated a possible oncostatic property of melatonin on different types of tumors. Besides, experimental studies have documented that melatonin could exert growth inhibition on some human tumor cells in vitro and in animal
Phospholipid-mimic oxaliplatin prodrug liposome fortreatmentof the metastatic triple negative breastcancer .
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A phospholipid-mimic oxaliplatin prodrug (Oxalipid) was synthesized, which could self assemble into a liposomal nanostructure with a drug loading ratio as high as 27 wt%. Compared to free oxaliplatin, the resulting Oxalipid liposome displayed elongated blood
The clinical study of secondary cytoreductive surgery in thetreatmentof low grade serous ovariancancer
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Abstract: Objective: To investigate the therapeutic effect of secondary cytoreductive surgery in the patients with low grade serous ovariancancerand to analyze the influence of the postoperative quality of life. Method: We collected the clinical data of patients with low grade
Robotic prostatectomy versus brachytherapy for thetreatmentof low risk prostatecancer
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Materials and methods: From January 2012 to January 2014, 165 patients with low risk prostatecancer , prostate volume≤ 50 g, normal urinary (IPSS≤ 7 and mean flow rate≥ 15 mL/sec) and erectile functions (IIEF-5> 17) were enrolled and randomly assigned to the
Dose-dense Paclitaxel With Carboplatin for Advanced OvarianCancer : Is It a Feasible and EfficaciousTreatmentAlternative for Indian Women?
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The outcome in AEOC is improved by bevacizumab and dose-dense chemotherapy (DDCT), which has antiangiogenic and pro-apoptotic properties [1]. An incremental cost-effectiveness ratio of $401 088 versus $5809 per progression-free life-year saved favoured later,
Renal Pelvis, Ureter and UreteralCancer -Etiology, Epidemiology, Diagnosis andTreatment
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AbstractCancerhas become more common for its progress and has less chance of treatment . The identification and prevention ofcancerhas been a bit difficult. Among all the types of cancers ureteralcanceris a new arisingcancerwhich is mostly seen in women
Preparation and Evaluation of 5-Fluorouracil Loaded Microsponges forTreatmentof ColonCancer
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Abstract 5-Fluorouracil (5-FU) has a wide anticancer activity versus several types of solid tumors. The activity of 5-FU can be improved and its toxicity can be diminished by enhancing the relative specific accumulation in the tumor regions. The aim of this work was to develop Posterior reversible encephalopathy syndrome (PRES) is an urgent neurologic condition that is associated with white and gray matter vasogenic edema primarily in parietal and occipital lobes [1]. Clinical features usually involve headache, altered mental status,
A NOVEL APPROACH IN THETREATMENTOF ORALCANCER -GENE THERAPY AN UPDATE
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ABSTRACT Gene therapythe use of genes as medicineinvolves the transfer of a therapeutic or working copy of a gene into specific cells of an individual in order to repair a faulty gene copy. Many experiments have been done with respect to its application in
Polymeric Nanoparticles as Potential Carrier forCancerDiagnostic andTreatment
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Polymeric nanoparticles are particulate dispersions or solid particles with size in the range of 10-1000 nm. They represent a promising drug delivery system of controlled and targeted release. A number of polymeric NPs are in the preclinical phase for the delivery ofcancer
OF 6-METHYLENE ANDROSTENEDIONE TO EXEMESTANE, AN AROMATASE INHIBITOR USED FOR THETREATMENTOF BREASTCANCER
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ABSTRACT: Exemestane is an aromatase inhibitor widely used for thetreatmentof postmenopausal breastcancerpatients. Several precursors are used for its synthesis; however the final step is C-1 (2) dehydrogenation of the resultant steroid to yield
GLOBAL DYNAMICS OF A MODEL OF JOINT HORMONETREATMENTWITH DENDRITIC CELL VACCINE FOR PROSTATECANCER .
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Abstract. Advanced prostatecanceris often treated by androgen deprivation therapy, which is initially effective but gives rise to fataltreatment -resistantcancer . Intermittent androgen deprivation therapy improves the quality of life of patients and may delay resistance towards
Sociodemographic Factors and Quality of Life in Children and Adolescents underCancer Treatment
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Abstract The evaluation of quality of life in children and adolescents withcancerhas become an increasing necessity, because of the different areas of the patients and its families lives that get affected by this disease. The aim of this research was to determine the association CSE PROJECTS