Clinical application




The clinical application of the biopsychosocial model
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Howphysicians approach patients and the problems they present is much influenced by the conceptual models around which their knowledge is organized. In this paper the implications ofthe biopsychosocial modelfor the study and care ofa patient with an acute

Molecular classification and molecular forecasting of breast cancer: ready for clinical application
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Profiling breast cancer with expression arrays has become common, and it has been suggested that the results from early studies will lead to understanding of the molecular differences between clinical cases and allow individualization of care. We critically review

Continuous passive motion (CPM): theory and principles of clinical application
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Stiffness following surgery or injury to a joint develops as a progression of four stages: bleeding, edema, granulation tissue, and fibrosis. Continuous passive motion (CPM) properly applied during the first two stages of stiffness acts to pump blood and edema fluid

Basic biology and clinical application of specific cyclooxygenase-2 inhibitors
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Background The antiinflammatory, analgesic, and antipyretic actions of aspirin became well known during the years after its introduction. More recently, the beneficial effects of the antithrombotic actions of aspirin in atherosclerotic disease have been recognized (1). There

Clinical application and image interpretation in intracoronary ultrasound
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Miniaturized flexible ultrasound catheters provide detailed information on the vessel wall. They are an additional diagnostic evaluation technique, partly in the realm of coronary interventions in patients with coronary artery disease. Fluoroscopy and angiographic road Diagnosis of primary and secondary brain tumours and other focal intracranial mass lesions based on imaging procedures alone is still a challenging problem. Proton magnetic resonance spectroscopy (1 H-MRS) gives completely different information related to cellThe purpose of this paper is to review the basic science and clinical literature on scaffolds clinically available for the treatment of articular cartilage injuries. The use of tissue- engineered grafts based on scaffolds seems to be as effective as conventional ACI clinically Unlike antibodies, T cells are well suited to penetrate and destroy solid tumors. The T-body approach combines antibody recognition and T cells effector function. It is based on T cells expressing chimeric receptors composed of antibody-derived Fv or scFv as their

ACC/AHA guidelines for the clinical application of echocardiography: executive summary
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This document is a revision of the Guidelines for the Clinical Application of Echocardiography published in December 1990. This executive summary and recommendations appears in the March 1 199 issue of the loumal of the American

Liver regeneration mechanisms and models to clinical application
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Liver regeneration has been studied for many decades and the mechanisms underlying regeneration of the normal liver following resection or moderate damage are well described. A large number of factors extrinsic (such as bile acids and circulating growth factors) and THIS article outlines a new theory of cerebral amirn funct,ion which. I believe, has several advantages ovcr existing views. The physiological theory which has dominated the field for the past decade was sponsored particularly by Brodie and his colleagues at Bethesda. Noradrenaline is suggested Vagus nerve stimulation was performed experimentally for the first time more than 150 years ago. In the 1980s and 1990s, vagus nerve stimulation was shown, both in the anesthetized and in the conscious animal, to exert marked antiarrhythmic effects, particularly during acute

Principles and clinical application of the locking compression plate (LCP)
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The principle of the locking compression plate (LCP) is represented by the combination of two completely different anchorage technologies and two opposed principles of osteosynthesis in one implant it combines the principles of conventional plate

Clinical application of cDNA microarrays in oncology
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ABSTRACT DNA microarrays represent an important new tool to analyze human tissues. The technology enables investigators to measure the expression of several thousand mRNA species simultaneously in a biological specimen. This process, called transcriptional

The clinical application of outcomes assessment
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3. Subjective versus Objective, Qualitative versus Quantitative Tests, and Provocative Tests: WHAT DOES IT ALL MEAN. Steven G. Yeomans 4. Classification of Outcome Assessment Instruments Prospective epidemiologic data consistently show that elevated C-reactive protein (CRP) levels are associated with an increased risk of subsequent cardiovascular events in apparently healthy populations, and accumulating laboratory research is uncovering

Mathematical law of chaotic cardiac dynamics: Predictions for clinical application
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The purpose of this study was to develop a new diagnostic methodology for cardiac dynamics. A mathematical deduction of Box-Counting equation was made, to determine the mathematical relationship between the occupancy spaces of parts and the total object

Mesenchymal stem cells for the treatment of cartilage lesions: from preclinical findings to clinical application in orthopaedics
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Purpose The aim of this systematic review is to examine the available clinical evidence in the literature to support mesenchymal stem cell (MSC) treatment strategies in orthopaedics for cartilage defect regeneration. Methods The research was performed on the PubMed Abstract The California Verbal Learning Test (CVLT) is a popular clinical and research test that claims to measure key constructs in cogntive psychology such as repetition learning, serial position effects, semantic organization, intrusion, and proactive inteference. The Heat shock proteins (HSPs) are a large family of proteins with different molecular weights and different intracellular localizations. These proteins undertake crucial functions in maintaining cell homeostasis, and therefore they have been conserved during evolution

Chaotic cardiac law: Developing predictions of clinical application
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Cardiac chaotic dynamics have been evaluated from dynamic system theory, fractal geometry, and a power law that deduces all possible discrete chaotic attractors allowing the development of a diagnostic method with clinical application . To confirm the clinical

Selective removal of low density lipoproteins (LDL) by precipitation at low pH: first clinical application of the HELP system
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The first clinical application of a new extracorporeal procedure (HELP) for the selective elimination of low-density lipoproteins by heparin precipitation at acid pH is described. Plasma, obtained by filtration of whole blood through a 0.2 µ filter, is continuously mixed with

Clinical Application and Effects of the Forsus Spring A Study of a New Herbst Hybrid
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Background: The best known of the fixed functional appliances are the Herbst appliance and the Jasper Jumper . The Forsus spring is a new development which has been tested in a clinical study to establish when it can be used and to compare it with its predecessorsBy easily stimulating the ear with loud sound and recording on tonically contracted neck muscles, vestibular evoked myogenic potential (VEMP) test can reflect inner ear function other than the cochlea and semicircular canal. This expands the test battery for clinicians to

Prefabricated composite veneers: historical perspectives, indications and clinical application
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Veneering anterior teeth is a well-established technique, which was brought to Dentistry by Dr Pincus as early as 1937. From the mid-1970s, boosted by the development of composites and adhesive techniques, various concepts emerged including direct composite Background Non-unions of long bone fractures are a therapeutic and economic problem of increasing frequency. Aside from conservative treatment options such as ultrasound, impulse waves, and casts, the basic surgical options are autogenous cancellous bone We report preliminary results of imaging intracranial vascular malformations with time- resolved projection MRA after a bolus injection of contrast median before and after endovascular treatment. Projection angiograms are acquired with a slice-selective snapshot

Skeletal anchorage in orthodontics basics and clinical application
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This review article describes the basics and clinical applications of skeletal anchorage in orthodontics, namely: areas of indication, anchorage devices, insertion areas, indications, potential complications, and their use in growing patients. The areas for skeletal anchorage

Stem cells clinical application and perspectives
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Background: Augmentation of myocardial performance in experimental models of therapeutic infarction and heart failure has been achieved by transplantation of exogenous cells into damaged myocardium. The quest for suitable donor cells has prompted research This review summarizes clinical application of adenosine and adenosine 5′-triphosphate (ATP) in pain conditions. Investigations have been performed in patients with acute perioperative pain or chronic neuropathic pain treated with intravenous adenosine or ATP

The late phase of preconditioning and its natural clinical application gene therapy
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There is little doubt that the discovery of ischemic preconditioning (PC) has been one of the fundamental milestones in the field of ischemic biology in the past 20 years. The purpose of this article is to review the pathophysiology and molecular basis of the late phase of

Ultrasensitive prostate-specific antigen assays and their clinical application
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The contributions of Stamey in the area of prostate cancer diagnosis, monitoring, and treatment and in the prostate speciļ¬c antigen (PSA) literature are numerous and noteworthy. 1 His accompanying Opinion article deals with aspects of analytical

Targeting GRPR in urological cancers from basic research to clinical application
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Gastrin releasing peptide (GRP) is a regulatory peptide that acts through its receptor (GRPR) to regulate physiological functions in various organs. GRPR is overexpressed in neoplastic cells of most prostate cancers and some renal cell cancers and in the tumoral vessels of

Interleukin-27: biological properties and clinical application
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Abstract Interleukin (IL)-27 is a novel cytokine secreted by stimulated antigen-presenting cells. Initial studies on the biology of IL-27 provided evidence for its role in the initiation of TH 1 responses; however, subsequent work has indicated that IL-27 has broad inhibitory effects

Clinical application of shock wave therapy (SWT) in musculoskeletal disorders
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Currently the application of shock wave therapy (SWT) in musculoskeletal disorders has been primarily used in the treatment of tendinopathies (proximal plantar fasciopathy, lateral elbow tendinopathy, calcific tendinopathy of the shoulder, and patellar tendinopathy, etc.)

Physical-mathematical diagnosis of cardiac dynamic on neonatal sepsis: predictions of clinical application
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Introduction: new diagnosis and physical-mathematical predictions have been developed by dynamic systems theory in adults. Also there were developed mortality predictors for neonates with sepsis based on heart rate variability measures. Objective: to predict neonatal The bowel sounds of 21 patients with mechanical obstruction of the intestine were studied. A computer analysis of bowel sounds was performed using a signal processor. Bowel sounds of patients were classified into 3 types (Types I, II, and III) based on the histograms, although

Guideline for the clinical application documentation and analysis of clinical studies for regional deep hyperthermia
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Objectives These guidelines contain recommendations for the implementation of quality- assured hyperthermia treatments. The objective is to guarantee an internationally comparable and easily understandable method for hyperthermia treatment and for the

Clinical application of motion-onset visual evoked potentials
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The results of motion-onset visual evoked potentials and pattern-reversal visual evoked potentials were compared in 5 adults with amblyopia, in 13 patients with unilateral retrobulbar neuritis and in 62 patients with multiple sclerosis. While the pattern-reversal

Clinical application of self-expandable metallic stent for treatment of colorectal obstruction caused by extrinsic invasive tumors
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Purpose The purpose of this study was to extend the application of self-expandable metallic stents by investigating their usefulness in treating colorectal obstructions caused by unresectable extrinsic tumors. Methods From January 2000 to November 200 a total of 60