lung cancer screening


The only recommended screening test for lung cancer is low-dose computed tomography (also called a low-dose CT scan). Screening is recommended only for adults who have no symptoms but are at high risk. … Doctors recommend a screening test to find a disease early, when treatment may work better.

Lung cancer screening : the Mayo program
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The National Cancer Institute has sponsored three randomized controlled trials of screening for early lung cancer in large, high-risk populations to determine whether (1) lung cancer detection can be improved by adding sputum cytological screening every 4 months to chest

Benefits and harms of computed tomography lung cancer screening strategies: a comparative modeling study for the US Preventive Services Task Force
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Background: The optimum screening policy for lung cancer is unknown. Objective: To identify efficient computed tomography (CT) screening scenarios in which relatively more lung cancer deaths are averted for fewer CT screening examinations. Design: Comparative

Lung cancer screening with sputum cytologic examination, chest radiography, and computed tomography: an update for the US Preventive Services Task Force
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Background: Lung cancer is the leading cause of cancer -related death in the United States and worldwide. No major professional organizations, including the US Preventive Services Task Force (USPSTF), currently recommend screening for lung cancer . Purpose: To

Lung cancer screening
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Advances in imaging technology have ushered in a new era for lung cancer screening in high-risk individuals using computed tomographic (CT) scans. Although most published studies are nonrandomized observational cohorts of volunteers, the ability of CT scans to

A pause, progress, and reassessment in lung cancer screening
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A troublesome problem in screening for lung cancer is the definition of a high-risk population the population that could best benefit from lung cancer screening . The I-ELCAP study included more than 3 000 subjects who were at risk for lung cancer because they

Screening for lung cancer
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Lung cancer is the commonest cause of death from cancer in both men and women, with approximately 152 000 new cases and 139 000 deaths in 1988. The incidence and mortality rates are increasing rapidly in women. Two main tests have been used to screen for lung

Risk-targeted lung cancer screening : a cost-effectiveness analysis
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Background: Targeting low-dose computed tomography (LDCT) for lung cancer screening to persons at highest risk for lung cancer mortality has been suggested to improve screening efficiency. Objective: To quantify the value of risk-targeted selection for lung cancer

Present strategy of lung cancer screening and surgical management
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Previous lung cancer screening trials in the United States (US) employing chest X ray and sputum cytology did not demonstrate reductions in lung cancer mortality. However, recent case control studies in Japan demonstrated a decrease in lung cancer mortality in the

Identifying patients for whom lung cancer screening is preference-sensitive: a microsimulation study
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Background: Many health systems are exploring how to implement low-dose computed tomography (LDCT) screening programs that are effective and patient-centered. Objective: To examine factors that influence when LDCT screening is preference-sensitive. Design

Screening for lung cancer by imaging: the Nelson study
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The NELSON trial is the first randomised lung cancer screening trial in which pulmonary nodule management is based on volumetry. This led to considerably less falsepositive referrals compared to other lung cancer screening trials, with very high negative predictive

Lung cancer screening : ready for prime time
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N ews from the National Lung Screening Trial (NLST) in November made headlines worldwide: A screening program had succeeded in cutting deaths from the worlds most lethal cancer by 20%. In this randomized, controlled trial, 5 000 current or former heavy

Screening for lung cancer with low-dose computed tomography: a systematic review to update the US Preventive services task force recommendation
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Background: Lung cancer is the leading cause of cancer -related death in the United States. Because early-stage lung cancer is associated with lower mortality than late-stage disease, early detection and treatment be beneficial. Purpose: To update the 2004 review of

Lung cancer screening debate continues despite international CT study results
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But the question of whether CT could detect tumors at an even earlier stage remained. In the late 1990s, Early Lung Cancer Action Program (ELCAP) investigators from Cornell scanned 000 highrisk people above age 60 with both a chest x-ray and low-dose CT. CT found

Screening for lung cancer
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At the completion of these studies in the late 1970s, none showed a reduction in lung cancer mortality because of screening using sputum cytology. Beyond this, because of the results of the MLP, CXR was also deemed not to be useful, even though the investigators

Volume CT for diagnosis of nodules found in lung – cancer screening
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Lung cancer , the most lethal type of cancer , accounted for more than 15 000 deaths in 2009 in the United States alone, 1 and the annual number of new cases is expected to exceed 33 000 by 2030. 2 Smoking-cessation and other tobaccocontrol measures have

Results of an open-access lung cancer screening program with low-dose computed tomography: the Gdańsk experience
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INTRODUCTION After primary prevention strategies, lung cancer screening is probably the most promising strategy for reducing lung cancer ‑related mortality. Among several screen‑ ing tools that have been tested, low‑dose comput‑ ed tomography (LDCT) appears to be the most

Better evidence about screening for lung cancer
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In October 20 the National Cancer Institute (NCI) announced that patients who were randomly assigned to screening with low-dose computed tomography (CT) had fewer deaths from lung cancer than did patients randomly assigned to screening with chest

Smoking habits were unaffected by CT screening at 1-year fol-low-up in the Danish Lung Cancer Screening Trial (DLCST)
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Background: The effect of low-dose computed tomography (CT) screening for lung cancer on smoking habits has not been reported in large randomised controlled trials. Method: This study evaluated the effect on smoking habits of screening with low-dose CT at 1-year follow

Commentary: Lung Cancer Screening -Progress or Peril
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Two reviews of lung cancer screening have been presented in this journal across the last two journal issues [ 2]. These articles differ markedly in content and tone. Lung cancer screening is a topic that has commanded considerable recent attention. This is a result, in

Lung cancer screening in Australia: progress or procrastination
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Editorials of a target population; false-positive rates; and best recruitment and uptake strategies. 9 The feasibility of chest CT screening in the Australian setting has already been demonstrated with the Queensland Lung Cancer Screening Study10 (long-term follow-up