ENGINEERING RESEARCH PAPERS

brain mapping research papers 2015 IEEE PAPER




Implementation of quantitative perfusion imaging techniques for functional brain mappingusing pulsed arterial spin labeling
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In functional magnetic resonance imaging (fMRI) of the brain, blood oxygenation level dependent (BOLD) techniques1 are typically used because they provide a high functional contrast to noise ratio. The analysis and interpretation of BOLD contrast functional data is

A noninvasive approach to quantitative functional brain mapping with H2 (15) O and positron emission tomography
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Summary: Positron emission tomographic (PET) measurements of regional cerebral blood flow (rCBF) with intravenously administered 150-labeled water and an adaptation of the Kety auto radiographic model are well suited to the study of functional-anatomical correlations

Brain mapping: the disorders
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Neuroimaging has become one of the growth areas in the clinical neurological sciences. The advent of CT scanners changed the entire strategy for diagnostic evaluation of patients with neurological disease. This trend was continued with the introduction of MRI scanners,

Robust multimodality registration for brain mapping
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Abstract: We present a robust intrasubject registration method for the synergistic use of multiple neuroimaging modalities, with applications to magnetic resonance imaging (MRI), functional MRI, perfusion MRI, MR spectroscopy, and single-photon emission computed

Brain mapping
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From cover photograph: Our understanding of brain systems has been and continues to be immeasurably improved by brain mapping. We are able to observe functioning circuits within detailed anatomical model in viva The cover design, by Arthur W. Toga, is intended to Topographic brain mapping of EEG and evoked potentials permits the display of spontaneous and event-related activity of the brain. This new method is superior to conventional polygraphy because of the topographic approach which delineates structural Summary The average reference introduces ghost potential fields at the latencies for which the integral of scalp-recorded potentials differs from zero. These spurious effects occur because the average reference is computed from a limited number of (scalp) electrodes

Brain mapping of Chinese speech prosody
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Speech prosody refers to melodic or suprasegmental features of an utterance (eg, pitch) that may signal a variety of linguistic and paralinguistic functions (Lehiste, 1996). Over the last quarter century, increasing attention has been focused on the roles of the left (LH) and

Functional mapping of brain areas implicated in auditory-verbal memory function
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SUMMARY Positron emission tomography measurements of regional cerebral blood flow (rCBF) were performed in normal volunteers during two auditory verbal memory tasks: a subspan and supraspan task. The difference in rCBF between tasks was used to identify

Brain mapping of visual evoked activity-topographical and functional components
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Abstract-Electroencephalographic (EEG) and evoked activity can be recorded non- invasively in order to monitor human brain activation online. Electrical fields are generated by large intracranial neural populations and spread to the scalp through volume

Color schemes to represent the orientation of anisotropic tissues from diffusion tensor data: application to white matter fiber tract mapping in the human brain
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This paper investigates the use of color to represent the directional information contained in the diffusion tensor. Ideally, one wants to take into account both the properties of human color vision and of the given display hardware to produce a representation in which

A graded task approach to the functional mapping of brain areas implicated in auditory-verbal memory
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Summary Positron emission tomography measurements of regional cerebral blood flow (rCBF) were performed in normal volunteers during a graded auditory-verbal memory task. Subjects were required to remember and then immediately, and freely, recall a series of

DTI parameter optimization at 3.0 T: potential application in entire normal human brain mapping and multiple sclerosis research
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Purpose An important goal of any noninvasive imaging modality, including DTI, is to minimize the scan time without compromising data quality. Thus, general knowledge of the tissue properties should guide the selection of the imaging parameters in order to attain

Synthesis of 131 I derivatives of indolealkylamines for brain mapping
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SUMMARY.-The synthesis and spectral properties of new 1 Introduction 1.1 Background fMRI is a means of measuring localised brain activity. It has been known since the late nineteenth century that the brain is spatially specialised by function [2]. But the regions associated with specific functions like speaking or motor activity are very In the course of human history, the concept of localization of the function within the brain is new. Early in the 19th century localization of brain function, including emotions and higher cognitive function, began as a pseudoscience. Franz Gall composed functional maps Abstract The International Cooperative Ataxia Rating Scale (ICARS) is a 100-point semiquantitative scale designed primarily to assess cerebellar dysfunction. However, little is known of the metric properties of this scale. We assessed the ICARS by rating the severity

Single pass sequencingand the physical and genetic mapping of human brain cDNAs
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We have performed single pass sequencing of 1,024 human brain cDNAs, over 900 of which seem to represent new human genes. Library prescreening with total brain cDNA significantly reduced repeated sequencing of highly represented cDNAs. A subset of

Mapping the human brain: past, present, and future
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The RECENT DEVELOPMENT of computer-aided medical imaging has generated a level of interest in the functional anatomy of the human brain unmatched since the latter part of the 19th century. For the first time, it is possible to record digitally, and then display and

Brain mapping: a short guide to interpretation, philosophy and future
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Quantitative studies of EEG and evoked response, including spectral analysis and topographic mapping, are becoming increasingly popular in clinical practice. Recent studies have shown these techniques to be useful in cerebrovascular disease, 1 2 epilepsy, 3 4

Kalman estimator-and general linear model-based on-line brain activation mapping by near-infrared spectroscopy
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Abstract Background: Near-infrared spectroscopy (NIRS) is a non-invasive neuroimaging technique that recently has been developed to measure the changes of cerebral blood oxygenation associated with brain activities. To date, for functional brain mapping

Optimization of brain conformal mapping with landmarks
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To compare and integrate brain data, data from multiple subjects are typically mapped into a canonical space. One method to do this is to conformally map cortical surfaces to the sphere. It is well known that any genus zero Riemann surface can be conformally mapped to a First, I want to thank Avison for taking the time to write his critique of my book. He and I agree on many of the main points of our discussion. However, he expresses some views that suggest that there are residual interpretive differences between us. Let me begin by Abstract. Functional magnetic resonance imaging is a technology allowing for a non- invasive measurement of the brain activity. Data are encoded as sequences of 3D images, usually few hundreds samples, each made by tens of thousands voxels, namely

Segmentation propagation from deformable atlases for brain mapping and analysis
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ABSTRACT Magnetic resonance imaging (MRI) is commonly employed for the depiction of soft tissues, most notably the human brain. Computer-aided image analysis techniques lead to image enhancement and automatic detection of anatomical structures. However, the

3D-relaxometry quantitative T1 and T2 brain mapping at 3T
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Methods: All imaging was performed on a Philips Intera 3T whole body scanner with an eight-element phase-array head coil. 6 normal controls were scanned for validation of the sequences. Two sequences were used for quantitative relaxation time analysis: a) T1-

18F-FDG PET mapping of regional brain activity in runners
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Background. To examine regional metabolic changes in the human brain induced by free running in upright posture. Methods. Experimental design: regional brain changes in glu cose uptake induced by running were examined by comparing brain images obtained by

Cellular-resolution activity mapping of the brain using immediate-early gene expression
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1. ABSTRACT Immediate-Early Genes are a class of genes that are rapidly up-regulated following neural stimulation. Due to their quality as potential activity markers in the CNS, they have been used extensively in functional mapping studies. At least three genes have

Brain mapping alterations in strabismus
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Congenital strabismus affects 3% of world population. Millions of persons suffer this condition, but still its origin or the reasons why not all patients respond to the traditional treatment are unknown. No long ago, it was believed that congenital strabismus had no relation The introduction of commercially available personal computers has made topo- graphic mapping of electrical brain fields easily accessible to the clinical neu- rophysiologist. Untill recently the visual observation of paroxysmal EEG discharges has been preferred over computerised

A novel EEG-based brain mapping to determine cortical activation patterns in normal children and children with cerebral palsy during motor imagery tasks
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Abstract. Purpose: The purpose of this study was to compare EEG topographical maps in normal children and children with cerebral palsy (CP) during motor execution and motor imagery tasks. Method: Four normal children and four children with CP (mean age 11.6

Non-invasive mapping of brain functions and brain recovery: applying lessons from cognitive neuroscience to neurorehabilitation
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Abstract. Modern cognitive neuroscience provides a powerful framework in which biological models of recovery and neurorehabilitation can be constructed and tested. The widespread availability, relatively low cost and informativeness of functional magnetic resonance

Brain electrical activity mapping in treatment resistant schizophrenics
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Quantitative studies of EEG and evoked response, including spectral analysis and topographic mapping, are becoming increasingly popular in clinical practice. Recent studies have shown the techniques to be useful in cerebrovascular disease (Ahn et al, 1987; Abstract Functional mapping studies using near-infrared spectroscopy have detected for the first time the existence of significant fluctuations in the concentration of cerebral oxygenated [oxy-Hb], and deoxygenated haemoglobin,[deoxy-Hb], during the resting period. The

Topographic Brain Mapping of EEG and Evoked Potentials in Chinese Normal and Psychiatric Patients-Preliminary Findings
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SUMMARY Computerised analysis of EEG and Evoked potential (EP) data yields more useful information than unaided visual inspection. Comparison between measures from patients and a database derived from normal controls increases the sensitivity and

Brain activation during language task contrasts in children with and without dyslexia: Inferring mapping processes and assessing response to spelling
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Abstract In the summer following grades 4 to 6, 18 children with dyslexia, who were randomly assigned to orthographic or morphological spelling treatment, and 21 controls, who were good readers and spellers, performed four sets of language tasks while their

Bayesian Identification of Problem-Solving Strategies for Checking the ACTR/Brain-MappingHypothesis
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Abstract. John R. Anderson proposed a correspondence between ACT-R modules and brain regions (brain mapping hypothesis). To check this conjecture we plan to compare model- generated blood-oxygen-level dependent (BOLD) signal curves with BOLD curves

Use of T 2-weighted susceptibility contrast MRI for mapping the blood volume in the glioma-bearing rat brain
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The aim of this work was to evaluate the potential of T2-weighted, steady-state susceptibility- enhanced contrast magnetic resonance imaging (MRI), to characterize brain tumor heterogeneity and tumor vascularization. In vivo T2-weighted MRI experiments were

How brain images reveal cognition: an ethnographic study of meaning-making in brain mapping practice
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Peer Reviewed Title: How brain images reveal cognition : an ethnographic study of meaning-making in brainmapping practice Author: Alac, Morana Acceptance Date: 2006 75 CHAPTER 4 I See What You Are Saying: Action As Cognition In fMRI BrainMapping

Tomographic mapping of brain intracellular pH and extracellular water space in stroke patients
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Summary: Functional images of regional intracellular pH (pH) and of fractional volume of extracellular water (FVECW) were obtained in IO patients with recent hemi spheric infarction (between IO and 19 days after onset of symptoms) using positron emission tomography (

Brain surface conformal mapping
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Abstract We propose a new variational method which can find a unique mapping between any two genus zero manifolds by minimizing the harmonic energy of the map. We demonstrate the feasibility of our algorithm by applying it to the cortical surface matching

synthesis in patients with irritable bowel syndrome using alpha-[^ 1^ 1C] methyl-L-tryptophan, positron emission tomography and statistical parametric mapping
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BACKGROUND: Irritable bowel syndrome (IBS) is the most common functional bowel disorder and has a strong predominance in women. Recent data suggest that the brain may play an important role in the pathophysiology of IBS in the brain-gut axis. It is strongly

Grand challenges in mapping the human brain: NSF workshop report.
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Workshop on Mapping and Engineering the Brain, held at Arlington, VA during August 13- 14, 2013. Three grand challenges were identified, including high spatiotemporal resolution neuroimaging, perturbation-based neuroimaging, and neuroimaging in naturalistic

New brain atlas-mapping the human brain in vivo with 7.0 T MRI and comparison with postmortem histology: will these images change modern medicine
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ABSTRACT: Human brain imaging with magnetic resonance at 7.0 Tesla (T) can reveal the brain's architecture with resolution equivalent to that obtained from thin slices in vitro. In vivo images can provide tissue type identification with a greater clarity than that available in

On-line brain mapping using fMRI and a Magnetic Resonance Compatible Hand-Induced Robotic Device (MR_CHIROD)
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Functional MRI (fMRI) methods combined with MR-compatible robotic devices are promising for monitoring and validating the effectiveness of stroke rehabilitation therapy (1). Previously, we reported the design, fabrication and preliminary testing of a novel, one degree of

Statistics of Brain Mapping
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The scientific aim of brain mapping is to investigate which regions of the brain are used when a subject is involved in a particular task, such as cognitive tasks, sensory stimuli, or memory challenges, or how brain function differs between different groups of subjects, Models of the mind, and the hope that these could be tied to neuroanatomical structures by brain maps, have motivated much of my research. Introspective modeling was my spontaneous response to the psychological wonderland I entered when, as a first-year graduate student, I

Brain expression quantitative trait locus mapping informs genetic studies of psychiatric diseases
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Abstract Genome-wide association study (GWAS) can be used to identify genes that increase the risk of psychiatric diseases. However, much of the disease heritability is still unexplained, suggesting that there are genes to be discovered. Functional annotation of

Multi-parameter mapping of the human brain at 1mm resolution in less than 20 minutes
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So called structural MRI of the human brain reflects not only the individual morphology, but also the intrinsic properties of tissue water related to the imaging process. The latter may more directly reflect changes in brain development and pathology. The goal of this study

Optimization of fast acquisition methods for whole-brain relative cerebral blood volume (rCBV) mapping with susceptibility contrast agents
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Fast gradient-echo magnetic resonance scan techniques with spiral and rectilinear (echoplanar) k-space trajectories were optimized to perform bolus-tracking studies of human brain. Cerebral hemodynamics were studied with full brain coverage, a spatial resolution

Functional metabolic mapping of the rat brain during unilateral electrical stimulation of the subthalamic nucleus
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Summary: The alterations in local metabolic activity of several anatomically distinct brain areas were investi gated by means of the quantitative autoradiographic 2-deoxY-D-[l-14C] glucose method in awake rats during uni lateral electrical stimulation of the subthalamic

Evaluation of the 11C02 positron emission tomographic method for measuring brain pH. II. Quantitative pH mapping in patients with ischemic cerebrovascular
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Summary: A practical method has been developed that, using IICOZ and positron emission tomography (PET), computes and maps (a)" effective pH"(pH,), a weighted average of intra- and extracellular pH, and (b)" clearance"(K\), product of blood flow and llCOZ ex traction.

Reflectometric mapping of microregional blood flow and blood volume in the brain cortex
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Summary: A reflectometric indicator-dilution method has been developed for mapping the parenchymal minute volume flow and blood content over tiny superficial areas of the brain cortex at 625 or 2500 locations, respectively. About 0.4 ml dextran-saline solution was This atlas and concise textbock by Maurer and Dierks is designed to promote knowledge of the applications of brain mapping techniques of EEG and evoked potentials in clinical neurophysiology and the functional location ofneuroelectric generators. It covers both the

Correlation time diffusion coefficient brain mapping: combined effects of magnetization transfer and water micro-kinetics on T1 relaxation
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Purpose: To develop a T1 relaxation theory incorporating the combined effects of magnetization transfer (MT)(Ref. 1) and water micro-kinetics–ie translational diffusion and molecular rotations (Ref. 3-5)--for the purpose of computing accurate correlation time

New techniques for 3D, high-resolution, whole brain mapping of murine vasculature
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METHODS: We conducted a series of experiments to determine the feasibility of perfusing the murine cerebral vasculature with different perfusates with the goal of obtaining complete vascular filling, optical validation, repeatability and high contrast to noise ratio in the µMRI The emergence of tomographic methods for mapping changes in regional cerebral metabolic activity in humans has led to an explosion of brain mapping studies. Implicit in these studies is the idea that the neural activity underlying at least some behaviors or

Brain mapping of developmental coordination disorder
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This chapter discusses the brain mapping of developmental coordination disorder (DCD). DCD is a neurological disorder characterised by impaired motor coordination and impaired performance of daily activities that require motor skills. In the Diagnostic and Statistical

Fast T1 mapping of the brain at 7 T with RF calibration using three point DESPOT1 method
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Materials and Methods: The study was conducted using a GE (General Electric) Signa 7T whole-body MRI scanner. The system is equipped with a Twin-Speed gradient system and a dynamically detunable birdcage transmitting coil. A whole-brain 16 channel receiver array

Perceptual dialectology. Mapping the geolinguistic spaces of the brain
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Nothing could be easier than ordinary cartography; find out where something is; show it on a map. Even things that aren't physically there can be assigned coordinates and represented as points or boundaries. And human factors people who believe this or that or act this or Summary. Background. Longitudinal relaxation time (T 1) map generation from human brain slices renders possible the in vivo follow-up of the changes in T 1 values during the course of several pathologies such as stroke, multiple sclerosis, traumatic brain injury etc. T 1

Cognitive Ontologies: Mapping Structure and Function of the Brain from a Systemic View.
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Rapidly developing research in neurophysiology has challenged classical cognitive models based on beha- vioral evidence. Studies looking more closely at the relationship between cognitive function and the brain structure have shed new light on how the mental processes are

THE EFFECTS OF A BRAIN-BASED LEARNING STRATEGY, MIND MAPPING, ON ACHIEVEMENT OF ADULTS IN A TRAINING ENVIRONMENT WITH
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Page 1. V8/r THE EFFECTS OF A BRAIN-BASED LEARNING STRATEGY, MIND MAPPING, ON ACHIEVEMENT OF ADULTS IN A TRAINING ENVIRONMENT the relationship between Mind Mapping and brain hemisphere dominance and this needs to

A wirelessly-activated Parylene electrothermal valve for mapping brain function in freely moving subjects
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ABSTRACT The first normally-closed Parylene valve operating on electrothermal principles for rapid and wireless drug delivery was designed, fabricated, modeled, and tested. This valve is a key component of an implantable microbolus infusion pump (MIP) for

Mapping the neural substrate underlying brain stimulation reward with the behavioral adaptation of double-pulse methods
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SYNOPSIS Behavioral adaptations of double-pulse methods-primarily collision and refractory period tests-have been employed to unveil the electrophysiological and anatomical characteristics of neural networks of known function. These paradigms are

Mapping crossing fibres of the human brain with spherical deconvolution: Towards an atlas for clinico-anatomical correlation studies
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Methods: Diffusion MR data were acquired from 5 normal brains on a 3T GE Signa HDx TwinSpeed system (General Electric, Milwaukee, WI, USA) with the following parameters: voxel size 2.4 x2. 4x2. 4 mm, matrix 128x128, slices 60, NEX 1, TE 90 ms, b-value 3000 s/

3D Mapping in the Brain
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Maps in rats and bats.(Right) As a rat is navigating in 2D space, there is strong electrical activity in hippocampal place cells and grid cells in the medial entorhinal cortex accompanied by theta-band oscillations.(Left) As a bat navigates in 3D, there is low-

Immunofluorescent mapping of cannibinoid CB1 and dopamine D2 receptors in the mousebrain
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G protein coupled receptors (GPCR) represent the largest protein family with over 1000 target for the majority of current pharmaceuticals (1). Alterations in GPCR expression have been associated with several disease processes.

Cloning, mapping, and expression of a novel brain-specific transcript in the familial dysautonomia candidate region on chromosome 9q31
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Familial Dysautonomia (FD) or Hereditary Sensory and Autonomic Neuropathy Type-III (HSANIII) is an autosomal recessive disorder affecting the development and survival of sensory, sympathetic, and some parasympathetic neurons with progressive neuronal

Brain electrical activity mapping (BEAM) in patients who commit violent crimes: Are bitemporal abnormalities a characteristic
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Recently a federal judge, 3 Judge Kenneth Ripple of the 7th US District Court of Appeals in Chicago, considered the case of whether or not to continue anti-psychotic drugs or injectable Prolixin for a federal prisoner who was sentenced to 10 years in prison after

Formulation of Topographical Mapping in Brain with a Synchronous Neural System
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Abstract:-Formulation of a neural system is presented for topographical mapping in brain. Composition of a system is first given to receive and analyze random pulse sequences with sensors set at corner points of a cube. An algorithm is obtained to discriminate multiple

In vivo mapping of fiber pathways in the Rhesus monkey brain.
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Abstract: The study of complex fiber systems in relation to the cognitive abilities of humans is a long-standing challenge for neuroscientists. With the development of diffusion tensor imaging (DTI) it is now possible to visualize large fiber bundles non-invasively. The The highly ordered neuronal projections from the retina to the tectum mesencephali (optic tectum) in several vertebrate groups have been intensively studied. Several hypotheses so far have been proposed, suggesting mechanisms to explain the topographical and

Functional mapping of the brain in vascular disorders
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This book contains the contributions to the symposium" Functional Mapping of the Brain in Vascular Disorders", held at the Thirteenth World Congress of Neurology, September 1-6, 1985 in Hamburg, FRG. I have to thank the contributors to this symposium for submitting

Nonparametric mixture modeling for mapping of brain activation using functional MRI data
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In conventional hypothesis based fMRI analysis, usually the analysis is based purely on the null hypothesis. It is difficult to construct a specific alternate hypothesis and the distribution of the test statistic under the alternate hypothesis is usually difficult to compute since the

Quantitative T1 mapping at 7 Tesla identifies primary functional areas in the living humanbrain
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Results: Figure 1a shows a coronal view of the quantitative T1 map at the level of the central sulcus. The arrows mark the transition zone between primary motor cortex M1 and somatosensory cortex. This decrease in T1 visible on the precentral gyrus (PrG) reflects

Mapping functional changes in rat brain in response to altered serotonergic function using BOLD fMRI
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Dysfunction in the brain serotonergic (5-HT) system is thought to underlie human depression1. Selective Serotonin Re-uptake Inhibitors (SSRIs) are widely used antidepressant drugs whose therapeutic onset are delayed for several weeks whilst



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